The iMONITRAF! Best Practice Guide shows several opportunities for the harmonisation of existing regional measures. However, it also becomes clear that regional measures have a limited potential to reduce the negative impacts from transalpine transport. Especially in the sensitive environment of the Alpine Space, the best-available-technology approach is an important concept for the further development. The incentives from existing regional measures are however not sufficient to fully use the potentials from new technologies. Also, the Best Practice Guide has made clear that even comprehensive policies have up to now not been successful in limiting a further growth of traffic volumes or in leading to a long-lasting change in the transport sector.